The De Simone Formulation unparalleled and certified by its inventor

Cutting-edge probiotic products for gut health

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Probiotici Formulazione De Simone

Science speaks for itself

The De Simone Formulation in CDS22-formula is the only probiotic formulation recommended and recognized by name in the guidelines of the American College of Gastroenterology (AGA) for the management of gastrointestinal disorders (Olleik et al., Gastroenterology, Vol. 164, No. 6, 2023).

The European Crohn’s and Colitis Organization (ECCO) has also included the De Simone Formulation in its guidelines for managing intestinal disorders (ECCO, ECCO News, 2023).

CDS22-formula is highly effective in the dietary management of various gastrointestinal conditions. Backed by extensive scientific evidence, including over 200 peer-reviewed articles and more than 80 controlled clinical trials, its benefits observed in clinical studies are replicable in daily use.

Why does it work?

Not all probiotics are the same. The overall biological action of a probiotic is not merely the sum of its individual components but rather the result of a complex network of interactions—both among the microorganisms within it and between these microorganisms and the human host. Unlike many other products on the market, the clinical results of CDS22-formula speak louder than any technical description.

CDS22-formula combines 8 carefully selected bacterial strains, chosen for their biochemical and enzymatic profile, and specifically blended in precise proportions to act synergistically on the physiology of the human gastrointestinal system.

It is crucial to highlight that the production of the De Simone Formulation belongs to the field of biology, not chemistry, as the bacteria at its core are living organisms. Cultivating them requires advanced scientific expertise and highly specialized know-how, which remains protected as an industrial trade secret.

The unique and advanced know-how developed by Prof. Claudio De Simone, including proprietary industrial secrets, contributes to the exceptional efficacy of CDS22-formula, making it extremely difficult for others to replicate or produce an identical or functionally equivalent product.

Backed by strong scientific evidence, CDS22-formula is highly effective in the dietary management of dysbiosis and other gastrointestinal conditions, delivering clinically proven and reproducible results.

Formulazione De simone
Formulazione De simone

CDS22-formula supports the dietary management of acute and chronic intestinal dysbiosis.

benefits

Managing intestinal dysbiosis

Intestinal dysbiosis is a condition in which the natural balance of microorganisms in the gut is disrupted, leading to a range of gastrointestinal disturbances. Controlling dysbiosis is essential for maintaining digestive balance and improving overall well-being.

Immediate and long-lasting gut flora restoration

CDS22-formula is ideal for both acute and chronic episodes of intestinal dysbiosis. It is particularly suited to supporting gut flora balance, which, when disrupted, can manifest as temporary or chronic intestinal discomfort. These imbalances may lead to accelerated transit, impacting daily activities and restful sleep.

Variety of Dosages

Available in multiple formats and dosages to meet individual dietary needs, CDS22-formula offers flexibility for healthcare professionals to determine the most appropriate supplementation regimen for each patient.

The original formulation

CDS22-formula is the original De Simone Formulation, a unique blend of proprietary bacterial strains designed to maximize its effectiveness in restoring gut flora balance. These strains are cultivated and preserved in proprietary Master Cell Banks, ensuring purity, quality, and consistency in every batch.

Guaranteed Safety

Each dose undergoes rigorous testing to ensure maximum efficacy and safety. With a short, controlled supply chain approved by the inventor, CDS22-formula upholds the highest quality standards from raw materials to final packaging.

Unmatched value

CDS22-formula offers superior quality at a better price than other probiotics with comparable bacterial concentrations. Efficient production and direct cost control allow us to provide a more affordable solution without compromising quality.

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