The De Simone Formulation in CDS22-formula is the only probiotic formulation recommended and recognized by name in the guidelines of the American College of Gastroenterology (AGA) for the management of gastrointestinal disorders (Olleik et al., Gastroenterology, Vol. 164, No. 6, 2023).
The European Crohn’s and Colitis Organization (ECCO) has also included the De Simone Formulation in its guidelines for managing intestinal disorders (ECCO, ECCO News, 2023).
CDS22-formula is highly effective in the dietary management of various gastrointestinal conditions. Backed by extensive scientific evidence, including over 200 peer-reviewed articles and more than 80 controlled clinical trials, its benefits observed in clinical studies are replicable in daily use.
Not all probiotics are the same. The overall biological action of a probiotic is not merely the sum of its individual components but rather the result of a complex network of interactions—both among the microorganisms within it and between these microorganisms and the human host. Unlike many other products on the market, the clinical results of CDS22-formula speak louder than any technical description.
CDS22-formula combines 8 carefully selected bacterial strains, chosen for their biochemical and enzymatic profile, and specifically blended in precise proportions to act synergistically on the physiology of the human gastrointestinal system.
It is crucial to highlight that the production of the De Simone Formulation belongs to the field of biology, not chemistry, as the bacteria at its core are living organisms. Cultivating them requires advanced scientific expertise and highly specialized know-how, which remains protected as an industrial trade secret.
The unique and advanced know-how developed by Prof. Claudio De Simone, including proprietary industrial secrets, contributes to the exceptional efficacy of CDS22-formula, making it extremely difficult for others to replicate or produce an identical or functionally equivalent product.
Backed by strong scientific evidence, CDS22-formula is highly effective in the dietary management of dysbiosis and other gastrointestinal conditions, delivering clinically proven and reproducible results.
CDS22-formula supports the dietary management of acute and chronic intestinal dysbiosis.